Tuesday, June 07, 2011

Histopathology Colon --Hemorrhagic infarct



The lecturer's seeminly glib manner is due to trying to make the educational environment more acceptable to a serious condition. It could probably be done without, but, I am not the student necessarily or the professor teaching.


The important aspect of this video is that serious 'cell membrane' degradation is taking place. This is often noted in hemorrhagic colitis. It is called an infarct because the tissue is disrupted, the cell membranes are destroyed.


If these infarcts are occuring one week after infection that is what is causing higher mortality rates. With this current strain of bacteria these 'infarct' could be happening in the other organ's tissues due to the same process here. It is a complex picture both for the patient and for the investigators.

One full week of bacteria replication within the body before symptoms are known is a lot replication, that is why it is so difficult to beat this lousy bug out of existence in a treatment regime.  In addition, after a week laters it is a multi-organ involvement.  Kidneys.  There goes your filtration and increased blood pressure.  The patients are compromised severely.  Increased blood pressure CAUSES 'system degradation' and ultimately shock.  It is bad bacteria.