What will a hairdresser and masseuse be wearing for their clients' comfort. Think "chic."

Honey Keeper Professional Cotton Full Body Suit (click here)

The professional seeing many clients a day will have to own a clean and freshly laundered bio-protection suit to be changed with each client.

This is a beekeeper's suit and it was the closest image I could find to what professionals would look like in a world with COVID-19.

I just don't believe 63 testing kits released in one day by the federal government were thoroughly tested for safety and accuracy. Until there is higher confidence in the ability and accessibility of tests, this is the way the future is going to look.

I see this same type of UNIFORM for people working in meat processing plants. There is always vegetable protein for a country mired in disease, too.

But, for the public at large to move about freely, I see something like this in use. A launderable cotton suit with a hood or mask that will protect the wearer and others.

It is my understanding that double-layered cotton is the best fabric to use when purchasing a non-N95 mask. This is not an endorsement, simply an example.

Our GOTS® organic certified reusable Face Masks (click here)
are made with two layers of 100% organic cotton canvas and two simple tie straps. They do not use elastic or plastic. They are not particulate filtering N95 medical masks, but will provide protection and help inhibit the transmission of Covid-19. Limit 1 pack per household. Non-refundable. Our family pack comes with 4 adult and 4 children's masks. Current production time is 10 to 15 business days, plus additional 1-4 days shipping.

Buddism requires a person to be "mindful" of their surroundings and their actions. I recommend Americans slow down and be mindful of their movements and exposure. It may become second nature to everyone in time. But, a rushed and hurried life can also be a careless one, whereby we were used to being carefree. We are no longer carefree, but, careful.

==– by Gil Fronsdal, February 2006

While mindfulness (click here) can be practiced quite well without Buddhism, Buddhism cannot be practiced without mindfulness. In its Buddhist context, mindfulness meditation has three overarching purposes: knowing the mind; training the mind; and freeing the mind.

This is a new skill set that only is to be used when necessary.

This article is from the NIH in 1999. I don't know how far the idea of large scale production of monoclonal antibodies has been pursued.

Monoclonal Antibody Production, 1999 (click here)

National Research Council (US) Committee on Methods of Producing Monoclonal Antibodies.

Washington (DC): National Academies Press (US); 1999.

About 25,000 mAb (click here) are listed in Linscott’s Directory (1998–99). Most are produced in small quantities (less than 0.1 g) for bench-related research purposes (de Geus and Hendriksen 1998b). However, some have become commercially successful and so require a scale of production different from that usually experienced in research facilities. Commercial interests consider production scales of 0.1–10 g as small, 10–100 g as medium, and over 100 g as large. Commercial-scale production is generally performed to produce mAb for three purposes: diagnosis, therapy, and research on and development of new therapeutic agents....

Clots most likely triggered by cytolysis.

...As Oxley, (click here) an interventional neurologist, began the procedure to remove the clot, he observed something he had never seen before. On the monitors, the brain typically shows up as a tangle of black squiggles — “like a can of spaghetti,” he said — that provide a map of blood vessels. A clot shows up as a blank spot. As he used a needlelike device to pull out the clot, he saw new clots forming in real-time around it....

Besides this phenomenon, there is another entry in my reading that mentions the discovery of lung tissue that was a mass of tissue without any real function. That is more than likely cytolysis used by the virus to release the replicated virus from the cell.

Where is the vaccine that will end the ability for the virus to attach to healthy human cells, using them and destroying it's plasma membrane.

The virus is not only triggering inflammation in the immune response it is lysing cells that release new virus. The lysing is triggering the clotting cascade.

That is my taking on it.

Critical care of these patients may at time include supporting the patient with elements that provide for an intact clotting cascade. Running out of the elements of the clotting cascade will result in DIC (disseminated intravascular coagulation).

Basically, the SARS-CoV-2 RNA attaches to the ACE2 (angiotensin I converting enzyme 2 [ Homo sapiens (human) ] (click here))
site of the human cell to enter and deposit the RNA into the cell, the RNA uses the cell's DNA resulting in the replicated virus. The replicated virus has to get out of the cell to continue the infection process, it destroys the human cell plasma membrane, hence, destroying the cell. The immune reaction of the human body causes inflammation and clotting to address cell destruction. Cell destruction (lysis) releases chemical components that alert the body's immune response and blood clotting.

...We show that SARS-CoV-2 S uses ACE2 (click here) to enter cells and that the receptor-binding domains of SARS-CoV-2 S and SARS-CoV S bind with similar affinities to human ACE2, correlating with the efficient spread of SARS-CoV-2 among humans....SARS-CoV-2 S glycoprotein harbors a furin cleavage site at the boundary between the S1/S2 subunits...murine polyclonal antibodies potently inhibited SARS-CoV-2 S mediated entry into cells...

Until the vaccine:

Custom Polyclonal Antibody Production (click here)

Free antigen design for customized application-specific polyclonal antibody.

We provide customized services for producing application-specific polyclonal antibodies used in your research. Leverage our years of experiences in polyclonal antibody production: from antigen design, immunogen preparation, antibody development, antibody purification, modification, validation, to immunoassay development.

Taking COVID-19 and the virus that causes it too lightly will mean many more disabled Americans.

Blood clots are coming to the foreground of this virus. This is a lot more than the flu.

April 24, 2020
By Ariana Eunjung Cha

...The patient’s chart appeared (click here) unremarkable at first glance. He took no medications and had no history of chronic conditions. He had been feeling fine, hanging out at home during the lockdown like the rest of the country, when suddenly, he had trouble talking and moving the right side of his body. Imaging showed a large blockage on the left side of his head.

Oxley gasped when he got to the patient’s age and covid-19 status: 44, positive.

The man was among several recent stroke patients in their 30s to 40s who were all infected with the coronavirus. The median age for that type of severe stroke is 74....

The statistics regarding this phenomena is important for anyone doing the research. Blood types and body chemistry (full chemical profile) including nutritional status for components that create the very clotting cascade can be part of all that for any pattern. It there a low level of vitamins and minerals in these victims of COVID-19?

April 22, 2020

New York — As the novel coronavirus (click here) spread through New York City in late March, doctors at Mount Sinai Hospital noticed something strange happening to patients' blood.

Signs of blood thickening and clotting were being detected in different organs by doctors from different specialties. This would turn out to be one of the alarming ways the virus ravages the body, as doctors there and elsewhere were starting to realize.

At Mount Sinai, nephrologists noticed kidney dialysis catheters getting plugged with clots. Pulmonologists monitoring COVID-19 patients on mechanical ventilators could see portions of lungs were oddly bloodless. Neurosurgeons confronted a surge in their usual caseload of strokes due to blood clots, the age of victims skewing younger, with at least half testing positive for the virus.

"It's very striking how much this disease causes clots to form," Dr. J Mocco, a Mount Sinai neurosurgeon, said in an interview, describing how some doctors think COVID-19, the illness caused by the coronavirus, is more than a lung disease. In some cases, Mocco said, a stroke was a young patient's first symptom of COVID-19....

I am thinking that victims of the clotting issue have poor quality food intake and as a result have a low STORE of all the elements of a healthy blood system. If the virus has a demand of its own for certain nutritional stores in order to replicate, it may be using up the stores of the patient/victim. When the stores of the elements supplying the clotting cascade are reduced, the blood clotting is triggered.

IV lipids and parenteral nutrition.

Poor nutritional status is often found in the poor and elderly.

April 1, 2020
By Roni Caryn Rabin

Neurologists around the world (click here) say that a small subset of patients with Covid-19 are developing serious impairments of the brain.

Although fever, cough and difficulty breathing are the typical hallmarks of infection with the new coronavirus, some patients exhibit altered mental status, or encephalopathy, a catchall term for brain disease or dysfunction that can have many underlying causes, as well as other serious conditions. These neurological syndromes join other unusual symptoms, such as diminished sense of smell and taste as well as heart ailments.

In early March, a 74-year-old man came to the emergency room in Boca Raton, Fla., with a cough and a fever, but an X-ray ruled out pneumonia and he was sent home. The next day, when his fever spiked, family members brought him back. He was short of breath, and could not tell doctors his name or explain what was wrong — he had lost the ability to speak....