Although (click here) human experience with uranium spans more than 200 years, the 
LD50 for acute intake in humans has not been well established. Large 
acute doses of uranium can produce death from chemical toxicity in rats,
 guinea pigs, and other small experimental animals, with variation in 
sensitivity among species. However, there has never been a death 
attributable to uranium poisoning in humans, and humans seem to be less 
sensitive to both acute and chronic toxic effects of uranium than other 
mammalian species studied. Highly relevant data on uranium toxicity in 
humans are available from the experience of persons administered large 
doses of uranium for therapy of diabetes and from acute accidental 
inhalation intakes. Although the data on which to establish oral and 
inhalation acute LD50 for uranium in humans are sparse, they are 
adequate to conclude that the LD50 for oral intake of soluble uranium 
compounds exceeds several grams of uranium and is at least 1.0 g for 
inhalation intakes. For intakes of uranium compounds of lesser 
solubility, acute LD50 values are likely to be significantly greater. It
 is suggested that 5 g be provisionally considered the acute oral LD50 
for uranium in humans. For inhalation intakes of soluble compounds of 
uranium, 1.0 g of uranium is proposed as the provisional acute 
inhalation LD50.
Even Dick Cheney would approve of this method.
Even Dick Cheney would approve of this method.

 
