For Flint children experiencing pain on mobility (running, jumping, walking) there is research in regard the operation of acetylcholine and choline in the nervous system.

...In the midbrain, (click here) however, a 30% reduction in Ch levels was observed. Changes in specific activity of Ch and ACh were measured as a function of time in selected brain areas of rats infused with a radio-labeled precursor of Ch. Specific activities of ACh were not altered. Ch specific activities were, however, significantly elevated in all brain areas examined, as compared with age-matched control rats. The in vivo ACh turnover rate in cortex, hippocampus, and striatum was diminished by 35%, 54%, 51%, and 33%, respectively. These findings provide direct evidence for an inhibitory effect of lead exposure from birth on central cholinergic function in vivo. Since a significant reduction of body weight was found in those animals treated with lead acetate, the alteration of central cholinergic function may partially be attributed to malnutrition observed in the lead-exposed animals.

I am not saying the pain isn't from the very bones of the children reporting it, what I am saying is the picture is much bigger and I BELIEVE it is more connected with the nervous system and it's chemicals at the transmission points of stimuli of the nervous system.

The community needs a dedicated set of physicians, one for adults and one for children connected with the University of Michigan.

This is an example of dedicated solutions for a small population compared to the overall population. In Iceland there is something called a "Founders Effect." This does not effect Flint, however, the dedication to detect and cure ill effects of illness is successful. The Founders' Effect in Iceland has bred a genetic disorder that caused this wonderful country a national determined to solve.

...Iceland is well-suited for genomics research (click here) for a few reasons. The island's relative isolation has resulted in a population of approximately 320,000 that is almost entirely descended from a single family tree....

Iceland began their venture into genetic research long before the USA cast money at the mysterious genome. Iceland announced it's success in such research shortly after the USA began its research. The lesson is that other countries may have information regarding the maladies of Flint. A clinic dedicated to Flint residents can attach itself to a far larger data base that might facilitate a faster relief to these injuries caused by polluted water from the Flint River.

There are countries in this world that love their citizens beyond any other priority. Iceland is one of those countries. There should be no delay in providing such a dedicated clinic to Flint. 

Now, in regard to a child's pain. These young people can be effected by their growth plates in laying down bone, however, I suspect it is more due to the nervous system because the bone cells are replaced every six to eight weeks and with growth plates laying down fresh bone with bottled water, the pain should resolve in a reasonalbe time. However, from the descriptor I heard from Mom it sounds more like the child's nervous system. Obviously, Mom is not receiving pertinent information and certainly not enough treatment of her children. 

Flint desperately needs it's own clinic attached to the University of Michigan to initially help with immediate problems and to ultimately to solve the problems of these children and any adults.

THAT IS AN IMMEDIATE NEED that has to be provided by the State of Michigan because of the danger an elected Governor CHOSE to inflict on Flint due to fiscal problems. These people's lives and quality of life were bargained with; human rights violations are a result and the State of Michigan along with elected individuals and others in the private sector are to blame. The State of Michigan has to immediately bring relief to Flint and the responsibility toward these people will continue until their deaths after a very normal longevity. To the extent the EPA is responsible will carry responsibility as well.

GET IT DONE, NOW!!!!!!!!!!