Larson died on December 16, 1997 in Los Angeles as a result of complications arising from cerebral edema triggered by liver failure. According to her friend Astrid Young, Larson had been showing symptoms of depression and her fatal seizure "was in no small way related to her chronic use of Valium and Tylenol PM".
Larson is buried in Forest Lawn - Hollywood Hills Cemetery in Los Angeles.
A benefit concert was held in Larson's honor the following February, with tribute concerts staged on the tenth anniversary of her death in December 2007 and also the following year.
Nicolette Larsen died at the age of 45.
