Of course we all know about The Wright Brothers with their gas motored and manned airplane (1903)
Paul Kornu, the first piloted helicopter (1907)
Leo Baekeland, first synthetic plastic called Bakelite; smoke stakes (1907)
1908, the first Model T Ford was sold
Charles Franklin Kettering invents the first automobile electrical ignition system (1911)
Sir Frederick Grant Banting, Insulin (1922)